Blog

New review for Unifiram

Nootropics

We have updated overview article of Unifiram. 

Unifiram (CAS# 272786-64-8) is a substance that was reported in year 2000 to have similar properties to piracetam but more potent in a mouse passive avoidance test. However, unifiram has shown pro-cognitive effects for mice by preventing amnesia induced by scopolamine (muscarinic antagonist), mecamylamine (nicotinic antagonist), baclofen (GABA-B agonist), clonidine (alpha-2 agonist), NBQX (AMPA antagonist) in passive avoidance test. Read more about Unifiram.

Unifiram is also available in our shop.

Effects of yohimbine to mind

Nootropics, SARMs

Yohimbine is usually considered an agent that helps to reduce body fat, increase sexual desire and ability for men as well as a stimulant that may cause unpleasant adverse effect of anxiety together with elevation of blood pressure.

However, according to the literature, yohimbine has some other effects as well, including effects on cognition, memory and sleep that may be of interest. Yohimbine (30 mg) reduced errors on letter flank test [1]. A simple version of letter flank test that shows ability to filter out irrelevant stimuli from detecting target letter is available online [2]. However, it increases rapid response impulsivity and errors in a somewhat more complex immediate memory test that has numbers instead of a single letter; the used dosage was a comparable 30 mg dose for a 75 kg person. The problem that occurred with yohimbine was that the test subjects did not read the number thoroughly and prematurely thought that the number was similar to another number presented just before the current. The test is explained online [4] but is not freely available.

Interestingly, yohimbine seems to have a truly interesting sex-specific effects on both memory and cognition of fear. Without affecting learning, it interrupted ability of women to generalize from learned memories [5]. Furthermore, the effect of yohimbine for processing fear-related signals (alteration of amygdala activity) is opposite for men and women [6].

A small study with medical students as subjects used a low dose. It was found that yohimbine improved following cognitive abilities: reaction time (single choice, not multiple choice), critical flicker fusion threshold and working memory (as measured by 1-back and 2-back tests) [7]. However, during glucocorticoid treatment or during high stress, yohimbine may be counterproductive for higher, flexible thought: yohimbine and cortisol together may reduce goal-directed behavior in favor of habitual behavior [8].

 

References:

[1] https://www.ncbi.nlm.nih.gov/pubmed/15858063
[2] https://www.psytoolkit.org/experiment-library/flanker.html
[3] https://www.ncbi.nlm.nih.gov/pubmed/15866563
[4] http://www.impulsivity.org/measurement/IMTDMT
[5] https://www.ncbi.nlm.nih.gov/pubmed/28253079
[6] https://www.ncbi.nlm.nih.gov/pubmed/23380165
[7] http://www.sciencedomain.org/abstract/7854
[8] https://www.ncbi.nlm.nih.gov/pubmed/22836250

Credit card payments and new batch of products

SARMs online shop

We have added credit card payments to Enhancetech web shop. Also there are new batch of products available.

Credit Card payments doesn’t include direct payments, but after checkout specific instructions will be sent. There is still option for SEPA payments, which means easy and quite fast bank transfers in EU countries.

There is also updates in our stock. Currently we are out of YK11, Ibutamoren and NSI-189, rest of the products are available for ordering.

YK11 overview added

SARMs

We have added YK11 overview. YK11 is not much researched SARM, but it has interesting and different mechanism of action than other SARMs.

YK11 (CAS# 1370003-76-1) is a molecule with sterol skeleton similar to dihydrotestosterone (DHT). YK11 is not yet researched in humans, not much is known about it. YK 11 has a dual (selective male sex hormone receptor modulator / myostatin antagonist) mechanism of action. In addition to being a partial agonist of androgen receptor, it is an inducer of follistatin. Follistatin is an antagonist of myostatin, a protein that inhibits muscle growth.
Read more about YK11.
Enhancetech is providing 5mg YK11.

Enhancetech online shop is opened

Nootropics, SARMs, SARMs online shop

We have opened our online shop at ENHANCETECH.eu address. It is possible to buy all products provided by Enhancetech. 

Online shop for nhancetech products is now opened. All our customers can buy now our provided SARMs and other products.

Currently we are offering following products:
Ostarine (MK-2866)
Ligandrol (LGD-4033)
Ibutamoren (MK-677)
Cardarine (GW501516)

All products can be ordered with different ingredient amount.

 

Also we are pointing out, that all products are for research purposes. SARMs are not medicines or food supplements. Please read our sale terms also before buying from e-shop.